Quality & Testing Guides
Analytical Methods, COA Verification, and Purity Assessment Intelligence
Quality Guide Library
Comprehensive resources for evaluating peptide quality, from analytical methods to supplier assessment protocols.
Analytical Testing Guides
HPLC Testing Guide
High-Performance Liquid Chromatography fundamentals for peptide purity assessment. Understanding chromatograms, purity percentages, and what HPLC results actually tell you about peptide quality.
Mass Spectrometry Guide
Mass spec analysis for peptide identity verification. How MS confirms correct molecular weight and detects impurities, degradation products, and synthesis errors.
Endotoxin Testing Guide
LAL testing for bacterial endotoxin detection. Why endotoxin levels matter for injectable peptides and how to interpret EU/mg specifications on certificates of analysis.
Independent Testing Guide
Complete guide to third-party peptide testing. How to arrange independent verification, recommended laboratories, costs, and interpreting results from external analysis.
Certificate & Documentation Guides
How to Verify COAs
Comprehensive guide to Certificate of Analysis verification. Identifying legitimate vs fabricated COAs, red flags in documentation, and cross-referencing supplier claims with actual data.
Understanding Purity Specifications
What purity percentages mean and how they're measured. The difference between crude, desalted, and HPLC-purified peptides. Setting appropriate purity requirements for different applications.
Laboratory Accreditation Guide
Understanding lab certifications and accreditations. ISO 17025, GLP, GMP, and what these designations mean for testing reliability and result validity.
Supplier Quality Assessment
Quality Standards Comparison
How quality standards vary across supplier tiers. Comparison of research-grade, pharmaceutical-grade, and compounding pharmacy quality requirements and testing protocols.
Manufacturing Standards Guide
Peptide synthesis methods and manufacturing quality. SPPS vs LPPS, GMP manufacturing requirements, and how production methods affect final product quality.
Why Quality Assessment Matters
Quality verification is not optional in peptide procurement. Consider these realities:
- Purity Variance: Testing shows research peptide purity can range from 85% to 99%+ from different suppliers
- Contamination Risk: Improperly manufactured peptides may contain synthesis byproducts, metals, or bacterial contamination
- COA Fabrication: Some suppliers provide fabricated or recycled certificates of analysis
- Batch Variance: Quality can vary significantly between batches from the same supplier
- Research Validity: Impure peptides produce unreliable experimental results
Related Resources
Quality assessment connects directly to supplier evaluation and safety protocols.
Best Purity Rankings Safety Guides